[Have you learned how to make duck hot pot?】 _How to do_How to do

銆 愯 厯 楦 The 雌 哯 殑 锅 氭 桭 状 犲  浼 Hydrogen Jane 撋 楻 犆 慱 抱 曱 箞 鐞 歞 悘 傡 傘 握 傡 悍 傍 傍 傍 悍 悍 傍 揍 名 名 悍 傺 悍 悍 悍 揍 傍 悍 傍 揍 炍 悍 傍 悍 悍 揍 悍 傍 揍 傍 揍 掍 悍 悍 悍 悍 悍 悍 悍 悍 悍 悍 悍 悍 悍 悍 悍 悍 掍 掍 揍 掍
I can’t help it, I can’t help it, I can’t help it, I can’t help it, I can’t stop it, I can’t stop it, I can’t stop it, I can’t do it, I can’t do it, I can’t do it, I can’t do it, I can’t do it, I can’t do it.畠鐨勫仛娉曟湁寰堝绉嶏紝鍏朵腑鏈€涓虹粡鍏哥殑灏辨槸鑵婇腑鐏攨锛岃繖绉嶅仛娉曢潪甯哥畝鍗曟槗瀛︼紝浜轰滑杩樺彲浠ユ牴鎹嚜韬殑鍙e懗鍋忓ソ鍔犲叆鑾茶棔绛夐鏉愶紝浼氳鐏攨鏇村姞棣欓唶娴撻儊銆傛湁鎯冲鐨勬湅鍙嬩滑鍙互璇曚竴璇曪紝鐩镐俊涓€瀹氬彲浠ュ仛鍑虹編鍛崇殑鑵婇腑鐏攨銆備竴銆佽厞楦Institute: Can you tell me what you can do? If you ca n’t read it, you can read it if you ca n’t read it or not.殑姘寸儳寮€鍐嶆斁鑵婇腑鍘荤叜涓€浼氾紝鍚屾椂鏀惧嚑鐗囧鐗囧拰婊寸偣鏂欓厭鎴栫櫧閰掗兘鍙互杩欐牱鈙  幓 闄 よ 厞 楦  殑 寑 寮 寮 傗 Effectiveness共It ‘s hard to say what ‘s going on, what ‘s going on, what ‘s going on, what ‘s going on, what ‘s going on, what ‘s going on, what ‘s going on, what ‘s going on, what ‘s going on, what ‘s going on, what ‘s going on, what ‘s going on?鍐嶆斁涓婂嚑鐗囧鐗囧姞涓婃按鎴栧紑姘达紝寮€鐏儳鍒拌厞楦紑濮嬭蒋鍖栧嵆鍙紝锛堝涓嶅枩娆㈢櫧钀濆崪鍙互鏀惧ぇ浠嬭彍闄ゅ幓鍙跺熬鎶婁粙鑿滄鍒囨垚澶у潡锛夊叾浣欑殑浣愭枡鍙互鑷繁鍠滄鏀句粈涔堝氨鏀句粈涔堥兘鍙互锛屼富瑕佹潗鏂欏氨鏄厞楦拰鐧借悵鍗滄垨澶т粙鑿滐紝绠€鍗曚笉鐢ㄥお澶嶆潅涔This is the best way to make a detailed plan for the fortune-telling program. It ‘s a good idea to make a fortune-telling program.閮界編鍛筹紒浜屻€佽厞楦椃钘曠伀閿?銆 佞 鏉 閉 閉 鐑 鐢 ㄧ 姹 姘 村 厛 廛 嬧 堸 堏 1 忔 殂 宸 ﹀ 姸 屽 噺 嬺 诲 毀 區區 區 鏀 揗 逗 鐢 尽 叾 尣 卾 将 卾 叆 叾 叆 浜 涘  鐗 囷 绂 3 銆 丸 楢 楢  吙 鍜 屽  璗 囨 喏 鍏 ョ Number of the number of points concrete  细 商 啬 啩 啩閿紝 绾?涓皬鏃讹紱5銆佷笁銆佸洓鍒嗛挓鏃剁敤閿呴摬缈荤倰涓€涓嬶紱6銆佸皢楦吙鐨勬补浠藉井寰吀鐐掑嚭浜嗭紝 鍐嶅姞鍏ヨ幉钘曞潡鍜岄€傞噺鐨勫紑姘达紱7銆佺洊濂界洊锛?畁 х 啣 栜 叜 Ad?銆 人 倴 逦  紴 玴 璬 镞 淗 悗 掾 堡 鑹 尉 鎏 鎏 鎏 鎏 錏 麴 鎴 铴 凴 鎴 围 围 围 围 囏 囏 囏 囏 尭。 わ わ わ わ わ わWhat are you talking about?What is the best way to do this? + Ad?銆 佷 嫴 鑸  厞 楦 Fan Zhencheng鐓叉堡鍓嶄竴瀹氳娴告场锛屾渶鍚庢斁鐩愮殑鏃跺€欎竴瀹氳鍏堝皾灏濓紝 鍐嶆牴鎹疄闄呰€冭檻鏀剧洂鐨勯噺锛?2銆佺叢姹ゆ椂鎴戜滑浼氶€夋嫨绮夎棔锛屼篃灏辨槸鍚冭捣鏉ュ彛鎰熺矇绮夐潰闈㈢殑锛屾墍浠ョ矇钘曚拱鐨勬椂鍊欐敞鎰忎簡锛岃棔鑺傜煭鑰岀矖锛岃〃闈㈠厜婊戯紝钘曠毊鐣ュ甫榛勮鑹诧紝澶氬崐灏辨槸绮夎棔浜嗭紱绮夎棔涓€鑸瓟姣旇緝澶氾紱 3銆佺敤鐢甸キ鐓茬倴鐓堡鍝佹椂锛?鍏堢洿鎺ュ湪鐢甸キ鐓蹭腑鐓哥倰涓€涓嬭厞鍛筹紝鍐嶅姞鍏ヨ棔涓€璧风倴锛岃繖鏍风倴鐓嚭鏉ョ殑姹ゅ憟涔Chongchao?

[Hemorrhoids can eat peanuts]_Hemorrhoids_Peanuts_Can you eat

銆愮棓鐤兘涓嶈兘鍚冭姳鐢熴€慱鐥旂柈_钀借姳鐢焈鑳藉悆鍚?
Talking about the situation, arguing, arguing, arguing, father, father, father, father, father, father, father, father, father, mother, father, father, mother, father, mother, father, mother, father, mother, father, mother界濂紝杩欐牱鏃㈣惀鍏诲張涓嶄細鍥犱负鎷呭績澶栭潰鐨勯鐗╀笉瀹夊叏涓嶆暍鍚冧簡锛岃€屼笖鑺辩敓鏈夊緢澶氬仛娉曪紝钂哥叜閮藉彲浠ョ粰鎴戜滑韬綋甯︽潵鐨勮惀鍏讳篃涓嶄細缂哄け銆備絾鏄偅鏈夌棓鐤殑浜哄彲浠ュ悆鑺辩敓鍚楋紵浼氫笉浼氬韬綋鏈変激瀹筹紵 鎮f湁鐥旂柈鐨勪汉鏄彲浠ュ悆鑺辩敓鐨勩€傝姳鐢熻兘琛ョ泭鑴捐儍鍜岃ˉ涓泭姘斻€傚濡傛秷鍖栦笉鑹€佺粡甯稿悙娉绘垨渚跨浜哄+閮芥湁濂藉锛屽鍚冭姳鐢熻兘鏀瑰杽鑲犺儍鍔熻兘銆傛澶栵紝鑺辩敓鍙堣兘琛ユ皵琛€锛屽浜庝腑姘斾笉瓒冲強姘旇浜忔崯浜哄+鐗瑰埆鏈夊府鍔┿€?You will be able to see the details of the chain and the details. The details are as follows: the details are fine. The details are fine.g 宸 没 採 掑 掑 掄 掮 尮 尮 鰴 鐴 ㄥ 紑 姘 村 啉 娉 ¢ 椃 20 鍒 嗛 挓 , 鍙  Mutually bear the gong Ruo 潗 憕 瑕佹兂鍛抽亾鏇村ソ涓€鐐圭殑璇濅篃鍙互鍔犲叆閫傞噺鐨勫啺绯栨潵璋冨懗锛屾鍙舵槸涓€绉嶆€ф儏寰噳鐨勫彾瀛愶紝瀹冭兘澶熸帓鍑虹儹閲忥紝鍑夎銆佹琛€锛屽浜庝竴浜涘ぇ鑲犲唴鐏強浣撳唴鐑噺钑寸粨瀵艰嚧鐨勫ぇ渚垮嚭琛€鏈夐潪甯稿彂鐨勬晥鏋?妲愬彾鍚姼棣欑敊绫婚粍閰紝杩欑鐗╄川鑳藉闄嶄綆鎵╁紶姣涚粏琛€绠$殑鎬婚噺锛岃姣涚粏琛€绠″叿澶囨甯哥殑鎶垫姉鍔涘鍏冭绠℃甯哥殑寮规€э紝鍑忎綆閫氶€忔€ц€岃揪鍒版琛€浣滅敤銆傚彲瑙佸鍠濇鍙惰尪瀵硅韩浣撴湁寰堝ぇ鐨勫ソ澶? 鏈ㄨ€宠姖楹昏尪锛氬彇榛戞湪鑰筹紝榛戣姖楹诲悇涓や唤60g,涓€浠借鐐掔啛锛屽彟涓€浠界敓鐢紝涓€娆$殑璇濆彇20g鐢熷搧涓庣啛鍝侊紝鐢ㄦ哺姘村啿娉★紝娉″ぇ姒?5 闒 嗛 挓 鉄 牱 瀛?欩 欐 牔 涔 熷 彲 浠 ヤ 綔 純 尪 鍝 佹 潵 雲 殑 殑!杩欎袱绉嶇墿璐ㄩ兘鏄敇骞虫粙娑︿匠鍝侊紝鏈夊噳琛€姝㈣鐨勫姛鑳斤紝鍙堟湁娑︾嚗閫氫究鐨勬晥鏋滐紝鎵€浠ュ浜庝究绉樼殑鎮h€呬篃鍙互閫夋嫨姝よ尪!榛戣姖楹绘洿鏄己澶ф湁琛ョ泭绮捐鐨勪綔鐢紝澶氬枬鍙互璁╀綘涔屽彂鏄庣洰锛岀敓鐢ㄧ殑涓€浠借兘澶熻娌规€ф垚鍒嗕笉浼氬彈鎹燂紝杩欐牱鍒╀簬閫氫究锛岀啛鍝佷竴浠界殑璇濇棬鍦ㄧ敤浜庢琛€鏁涜!鎵€浠ユ湪鑰宠姖楹昏尪鍦ㄥ尰瀛︿笂瀵圭棓鐤嚭琛€銆佸ぇ渚跨缁撱€佽倹瑁傜瓑鐥囨湁闈炲父濂界殑鏁堟灉銆?

[How long can frozen meat be kept]_storage time_storage period

[How long can frozen meat be kept]_storage time_storage period

Frozen meat is a relatively common food. This is mainly because meat is easily spoiled if it is stored at room temperature, but if it is frozen, its shelf life will be greatly increased.

However, frozen meat cannot be eaten for too long, and generally, it cannot exceed six months.

Because frozen meat for more than six months has a very negative impact on human health!

First, how long can frozen meat be stored? According to nutritionists, the shelf life of frozen meat is 6 months. After the shelf life, the color of the meat turns yellow and the nutrition gradually decreases. Therefore, it is best not to freeze frozen meat for more than 6 months.

There is no problem in eating frozen meat at the shelf-life level. After the shelf-life, the meat tastes hard and the nutrition is reduced. If it is too long, it cannot be eaten again. It may be harmful to the body.

Also, fresh pork is best bought in a fresh-keeping refrigerator for one day before it is eaten. The fresher meat is not as delicious as it is. The meat must be allowed to drain sour and enter the mature period before it is delicious.

Second, the method of freezing meat The low-temperature storage method, that is, the cold storage of meat, is performed in a cold store or a refrigerator, and is the most practical method for storing meat and meat products.

Under low temperature conditions, especially when the temperature drops below minus 10 ° C, the moisture in the meat will form ice, resulting in an environment where bacteria cannot grow and develop.

But when the meat was thawed and thawed, the bacteria began to grow again due to temperature rise and leakage of gravy.

Therefore, when meat is stored at a low temperature, it must be kept at a low temperature until it is eaten or processed, otherwise the quality of the meat cannot be guaranteed.

Refrigeration of meat can be divided into two types: cold meat and frozen meat.

Third, the classification of frozen meat 1, chilled meat: mainly used for short-term storage of meat, usually reducing the temperature of the meat center to 0 ℃?
About 1 ° C.

The specific requirement is that before the meat is added to the cold storage, the temperature of the storage should be reduced to about -4 ° C. After the meat is stored, the temperature should be maintained at -1 ° C.
Between 0 ° C.

The pork is cooled for 24 hours and can be stored for 5?
7 days.

After cooling the meat, a dry film is formed on the surface, which prevents the growth of bacteria, slows the evaporation of water, and prolongs the storage time.

2. Frozen meat: The meat is quickly and deeply frozen, so that most of the water in the meat is frozen into ice. This kind of meat is called frozen meat.

Frozen meat is more resistant to storage than chilled meat.

Meat is generally frozen at temperatures below -23 ° C and stored at around -18 ° C.

In order to improve the quality of frozen meat and restore its taste and nutritional value after thawing, most cold storages currently use the quick-freezing method, that is, the meat is added to the quick-freezing room at -40 ° C, and the temperature of the meat is quickly reduced below -18 ° C, Then move into the refrigerator.

[Eating Chili Allergy]_ Chili Allergy _ How to Skin Care _ Skin Care Methods

[Eating Chili Allergy]_ Chili Allergy _ How to Skin Care _ Skin Care Methods

Chili is a very common vegetable in daily life. Chili is divided into many types. There are particularly spicy millet peppers that are suitable for use as ingredients. They are very flavorful and very tasty. However, some people are allergic to chili and eat chili.Allergic skin will grow granular rashes, or itching and redness.

Correct skin care after eating allergies to peppers. Use less cosmetics. Use some natural aloe vera slices, bitter gourd slices, banana slices. You can apply them on the surface. Cucumber slices are very hydrating and can soften the skin.Type skin care products reduce skin irritation. Want to completely improve the skin. Begin by strengthening your body and stay away from spicy food or seafood. Eat more grains, drink more honey, water, more fruits, and especially grape kiwi.

Eating spicy food is more likely to dry out the skin and make acne more common.

Pepper contains spicy ingredients. Excessive intake will cause skin sensitivity.

Method 1 for skin care of spicy people.

Three simple steps to increase skin resistance. If you want to eat spicy food and worry that peppers can damage the skin’s natural barrier and produce sensitive phenomena, then the most effective way is to increase the skin’s resistance through external forces.

The basic principle of nourishing skin is: supplement natural intercellular lipids to balance the humidity inside and outside the skin cell membrane.

2.

Dry skin is very harmful to Asian women.

51% of women in Japan have dry skin, while 61% of women in South Korea have dry skin. I wonder if Korean beauty prefers pepper.

If you have dry skin and can’t reduce the temptation of pepper, it is recommended to choose a moisturizing product containing pure natural vegetable fat, because the type of fat is very similar to the skin’s own sebum, which can quickly soothe and nourish the skin.

In fact, pepper also has skin beauty skills.

The substitution of peppers for skin damage is overdose, or your constitution is not suitable for eating too much.

In fact, moderate intake of peppers is also good for the skin.

Capsicum contains the most vitamin C in vegetables. Vitamin B, carotene, calcium, iron and other nutrients are very rich.

In addition, Japanese researchers have found that using spicy hormone to stimulate the sensory nerves that sense pain and burning in the skin, the sensory nerve endings secrete an enzyme that can activate apoptosis and prevent skin aging.

[How to eat green tofu]_How to make_Making method

銆愮豢璞嗚厫鎬庝箞鍋氬ソ鍚冦€慱濡備綍鍋歘鍒朵綔鏂规硶
This is the most important thing in the world. It’s hard to find the best way to do it. It’s very difficult to find out how to use it.You will be able to find out how to do it, if you want to use it, if you want to do it, you will be able to use it.This is the best way to learn how to do it when you are in the same place as you are doing it in a hot pot or in a hot pot.紝鏄禉姹熷崡閮ㄤ笌绂忓缓鍖楅儴涓€绉嶆瘮杈冨父瑙佺殑鏍戞湪锛岀豢璞嗚厫灏辨槸鐢ㄨ繖绉嶆爲鏈ㄧ殑鍙跺瓙缁忚繃涓€绯诲垪宸ヨ壓鍒舵垚鐨勩€傜豢璞嗚厫鐨勫埗浣滄柟娉曞綋鐒跺彧鏈夊彾瀛愭墠鏄埗浣滅豢璞嗚厫鐨勭湡姝e師鏂欍€傚亣濡備綘鏄釜鍠滄閲庤叮涔嬩汉锛屾渶濂芥槸浜茶嚜涓婂北閲囨憳锛屽彲浠ュ厜閲囧彾瀛愶紝涔熷彲浠ユ姌鍙栨灊鏉°€傚湪杩欓噷浣犱笉瑕佹湁鏉€楦”彇鍗典箣铏I’m sorry, I’m sorry, I’m sorry, I’m sorry, I’m sorry: I’m not sure what to do, I’m going to read it, I’m going to read it.The coefficients of the world are getting thinner and thinner. The following is the best way to go: the world’s best, the best way to do it, the best way to do it, the best way to do it.哥畝渚匡紝浠ヤ笅鏄豢璞嗚厫鐨勫埗浣滆繃绋嬶細涓€銆佸厛灏嗘柊椴滅殑缁胯眴鑵愬彾鎽樹笅鏉ワ紱浜屻€佸娓呮礂鍑犻亶锛堝ぇ閮ㄥ垎鏄噹鐢熺殑锛屼絾涔熸湁鍐滄埛绉嶆鐨勶級锛涗笁銆佹竻娲楀共鍑€涔嬪悗鍔犲叆閫傞噺鐨勬按锛屼互娌¤繃缁胯眴鑵愬彾涓哄噯锛岋紙鏈夋潯浠剁殑涔熷彲浠ョ敤鍐峰紑姘存洿鍗敓锛夊綋鐒舵按鐨勫灏戜篃鍐冲畾浜嗙豢璞嗚厫鍑濈粨鎴愬潡涔嬪悗鐨勮蒋纭害锛涘洓銆佸紑濮嬪弽澶嶆弶鎼擄紝鎶婄豢璞嗚厫鍙堕噷鐨勬眮娑叉悡鍑烘潵锛岀洿鍒版劅瑙夋湁鐐归粡绋犱负姝紱浜斻€佸ぇ姒傛弶鎼?0鍒嗛挓宸﹀彸锛屾劅瑙夋妸鍙跺瓙鎼撴垚娉ョ姸灏卞樊涓嶅浜嗭紱鍏€佹妸绋嶅井澶х偣鐨勫彾鐗囧拰鍙舵福鎹炶捣骞舵尋骞叉眮娑叉墧鎺夛紝鑰屼笉鑳界敤鎵嬫崬璧风殑鍙舵福鍒欑敤绾卞竷鎴栬€呰繃婊ょ綉杩囨护涓冦€佽繃婊ゅソ鐨勭豢璞嗚厫姹侀潤缃竴鏃侊紝鎶婁簨鍏堝啿娉″ソ鐨勭墮鑶忔按鍧囧寑鎼呮媽鍊掑叆锛堢墮鑶忔按涓昏鏄捣鍒板姞蹇嚌缁撶殑浣滅敤锛岀墮鑶忛噷鍚湁纰抽吀閽欙紝寤鸿閫夌敤鏈€渚垮疁鐨勪腑鍗庣墮鑶忥紝鑶忎綋鍛堢櫧鑹茬殑锛屽垎閲忓彧瑕佽姳鐢熷ぇ灏忓氨澶熶簡锛夛紱鍏€佸€掑叆鐗欒啅姘翠箣鍚庢寜鐓ч『鏃堕拡灏嗙豢璞嗚厫姹佸揩閫熸悈鎷屽潎鍖€锛屽ぇ姒傚崄鍦堝氨澶熶簡锛佸崄鍒嗛挓鍚庡氨鍙互鍝佸懗缇庨鍟︼紝锛堝鏋滄媴蹇冪豢璞嗚厫姹佹病鏈夊畬鍏ㄥ嚌缁擄紝鍙互鍦ㄤ腑闂存彃涓€鏍圭瀛愶紝鑻ョ瀛愮瑪鐩寸珫璧峰垯琛ㄧず瀹屽叏鍑濈粨锛岃嫢绛峰瓙渚х炕锛屽垯琛ㄧず杩樿鍐嶇瓑浼氾紝鎴栬€呮按鐨勬瘮渚嬭繃澶氾紝閫犳垚缁胯眴鑵愭眮纭害涓嶅锛屽亸杞紒锛変節銆佸畬鍏ㄥ嚌缁撳ソ鐨勭豢璞嗚厫灏卞彲浠ュ紑鍚冧簡銆傝懕鐑х豢璞嗚厫鈥滃ぇ钁辨槸涓€绉嶇豢鑹茬殑钄彍锛屾嵁鏈夐潪甯搁珮鐨勮惀鍏讳环鍊硷紝瀹冨惈鏈変赴瀵岀殑缁寸敓绱犲拰灏戦噺铔嬬櫧璐ㄣ€備竴浣嶈€佷腑鍖绘浘缁忚杩囷紝鐢锋€у悆浜嗗ぇ钁卞氨鍙互琛ヨ偩澹槼锛屽コ鎬у悆浜嗗ぇ钁卞垯鍙互鍑忕紦鐨偆琛拌€侊紝璧峰埌婊嬮槾琛ラ槼鐨勪綔鐢ㄣ€傚啀閰嶄笂钀ュ吇鍋ュ悍鐨勭豢璞嗚厫锛岀編鐨勪笉瑕佷笉瑕佺殑锛佲€濈敤鏂欙細涓绘湡 澶 ц 懕 1 镙 Silicone tank 愬 潡 (缁?湮 呮 渡 Adorable?Onion Honglai 1?翏 忓 奼 奦 $ 簿 0 銆?Oncoin?Quite steady?What are you talking about? 2 What are you talking about?銆傚噯澶囧洓鏂圭豢璞嗚厫涓€鍧楋紝棰滆壊濂界編锛屼笉鑸嶅緱鍒囧暒锛?What is the effect?銆?cm宸﹀彸鍘氬害鐨勬柟鐗囥€?銆傚噯澶囧ぇ钁辩墖锛岃懕澶氭斁浜涳紝濮滅墖锛屽叓瑙掍竴绮掓彁鍛炽€?銆傞攨涓儳澶氫簺娌广€?銆傚ぇ鐏皢璞嗚厫鐓庢垚涓ら潰閲戦粍锛屾敞鎰忓埆鐓庣硦浜嗭紒6銆傛崬鍑烘帶娌瑰鐢ㄣ€?銆傞攨涓暀搴曟补锛屾斁鍏ュ叓瑙掞紝濮滐紝澶ц懕锛岀倰棣欍€?銆 傛 斁 鍏 郏 ョ 厧 忂 界 殑 Puru 咫 厣 寑 劆 銆?銆傚€掑叆灏嗘病杩囬鏉愮殑姘达紝鐑у紑鍚庣洊鐩栧瓙灏忕伀鐐?闒 嗛 抓 銆?0銆傚姞鍏ョ洂锛岄浮绮撅紝鐢熸娊鍜屾按娣€绮夛紝澶х伀鐑ц嚦绮樼锛屽嚭閿咃紒11銆傝鐩樺紑鍚冿紝璞What are you doing? Do you have a lot of time? Do you have a lot of trouble? Do you have a lot of trouble? Do you have a lot of trouble? Do you have a lot of trouble

Hengrui Medicine (600276): PD-1 combined with FOLFOX4 for first-line treatment of advanced hepatocytes was approved for III clinical indications to expand product potential

Hengrui Medicine (600276): PD-1 combined with FOLFOX4 for first-line treatment of advanced hepatocytes was approved for III clinical indications to expand product potential

Investment Highlights Event: On July 17, 2019, the company announced that Carelizumab (SHR-1210) combined with FOLFOX4 versus placebo combined with FOLFOX4 is a randomized, parallel-controlled, double-blind, multi-lineThe Phase III clinical study of the center was approved by the State Drug Administration.

In addition, carelizumab (SHR-1210) combined with capecitabine and oxaliplatin sequential carelizumab combined with apatinib mesylate for advanced or metastatic patients who have not previously received 杭州桑拿网 systemic therapyRandomized, open-label, multicenter Phase III clinical study of gastric gastric cancer (GC) or gastroesophageal junction cancer (GEJ).

Carrelizumab combined with FOLFOX4 for first-line treatment of patients with advanced hepatocellular carcinoma has been approved for phase III clinical treatment, and there is a large space for first-line treatment of large diseases in China.

GLOBOCAN 2018 research shows that in terms of incidence, liver cancer patients account for the overall incidence of cancer4.

In terms of mortality, liver cancer accounts for 8 of the total cancer population.

2%, ranking second.

The burden of liver cancer disease is greater in men than in women, and complications are greater than overall.

The incidence of liver cancer in men was ranked 10th, and death was ranked 6th. Women were not ranked in the top 10, and death ranked 7th.

According to the China Cancer Report 2018, the number of new cases of liver cancer accounted for 9%.

59%, the incidence is ranked fourth.

PD-1 products have been approved for second-line treatment of liver cancer overseas, and are in the clinical stage in China.

At present, the first-line drugs for domestic liver cancer are approved by first-line molecular alternatives, such as sorafenib, Dorgemex, and regorafenib. The first-line treatment options for domestic liver cancer include the following: surgical resection (costs about 50,000—100,000), liver transplantation (usually tens of thousands to tens of thousands), blood vessel implantation (about 10,000), radiofrequency ablation (tens of thousands).

Nivolumab is currently approved for second-line treatment of liver cancer through the checkmate040 study.

Carelizumab is the fastest in the clinical progress of PD-1 in liver cancer in China.

Domestic PD-1 products have never been approved for listing in liver cancer, of which Carelizumab is in a leading position.

The FDA, the Chinese FDA, and the Chinese NMPA have approved the implementation of “Global, Multicenter Phase III Clinical Study of Carelizumab and Apatinib in the First-line Therapy for Advanced Liver Cancer”, replacing Sorafenib.

In the first-line treatment of patients with advanced hepatocellular carcinoma with carelizumab combined with FOLFOX4 compared with placebo and FOLFOX4, the phase II clinical trial data of SHR-1210 combined with FOLFOX4 in the first-line treatment of advanced hepatocellular carcinoma showed an effective ORR of 27.

3%, the disease control rate reached 72.

7%.

In addition to Karelizumab, Tislelizumab from BeiGene has entered the first-line treatment of hepatocellular carcinoma overseas. The Phase III Karelizumab combination regimen is used to treat advanced or metastatic gastric cancer (GC) or gastroesophageal junction cancer.Phase III was approved for further development of indications According to the 2015 China Cancer Data Report, there were 67 new cases of gastric cancer each year in the past.

90,000 cases and 49 deaths.

80,000 cases, with an average of nearly 1 per day.

20,000 people were diagnosed with cancer, of which esophagus, stomach and colon cancer accounted for nearly 40%.

Globally, nearly half of new gastric cancer patients and deaths occur in China.

At present, among the domestic PD-1 manufacturers, except for Hengrui, Cinda and BeiGene, the indications for gastric cancer have entered clinical stage III, and Junshi is currently in clinical stage II.

In addition to liver cancer and gastric cancer, Karelizumab is currently in clinical stage III in non-small cell lung cancer, nasopharyngeal cancer, and esophageal cancer. It is a leading country in China, with indications developed, and the product space will continue to increase.

Profit forecast and investment recommendations are based on the company’s stable operating style, certain product lines, and rich R & D pipeline reserves. We estimate the company’s operating income for 2019-2021 to be 225.

81, 290.

32, 363.

7 billion, net profit attributable to mother is 52.

1.3 billion, 67.

3 billion, 86.

25 ppm, an increase of 28 in ten years.

2%, 29.

1%, 28.

2%, corresponding to the PE of 56X / 43X / 34X, PD-1, pirlotinib, paclitaxel albumin and other heavy products on the market bring sales growth, rich research and development pipelines to provide continuous driving force for the company’s future development.

As a leader in the industry, the company benefits from the positive effects of the innovative drugs brought by the policy and the increase in industry concentration. Therefore, we maintain the “Buy” rating.

Risks suggest that the company’s drug bidding is lower than expected; the progress of drug review and 杭州桑拿网 approval is gradually expected; the progress of the R & D pipeline is gradually expected; and the export of preparations is lower than expected.

China Shipbuilding (600150) Company Dynamic Comment: Integration and Acceleration of the Final Assembly Listing Platform

China Shipbuilding (600150) Company Dynamic Comment: Integration and Acceleration of the Final Assembly Listing Platform

Event: On August 23, 2019, the company released its semi-annual report for 2019, and realized revenue of 97 in the first half of 2019.

73 ppm, an increase of 27 in ten years.

95%; net profit attributable to mother is 0.

4.5 billion, down 78 a year.

29%; net profit after deduction is 0.

8.3 billion, a reduction of 2 previously.

3.7 billion.

The revenue of 2019H1 is steadily increasing, and the net profit after deduction is substantially reduced. The company achieved revenue of 97H1 in 2019.

73 ppm, an increase of 27 in ten years.

95%, the highest increase in the past six months in ten years; net profit after deduction is -0.

US $ 8.3 billion, a significant reduction in losses previously2.

3.7 billion.

Among them, the main business ship repair / offshore engineering / power equipment / mechanical and electrical equipment revenue was 69.

85/4.

91/14.

09/7.

300,000 yuan, fluctuating 29 within a year.

68/379.

56/15.

63 / -1.

72pct, each business revenue accounted for 71.

47% / 0.

50% / 14.

41% / 7.

47% move 0 every year.

96/3.

68 / -1.

54 / -2.

26pct. The gross profit margin of each main business is 7.

79% /-0.

35% / 9.

08% / 9.

06%, ten years change -2.

53 / -0.

21 / -3.

59 / -2.

53 points.

The increase in the prices of major raw materials such as steel plates has led to a decline in the gross profit margin of the shipbuilding and repair business. The sales of diesel engines increased compared with the same period of the previous year to achieve an increase in revenue. However, due to changes in the product sales structure, the gross amount decreased compared to the same period of last year. The goal of “more than half of the time and half of the tasks” was fully realized, and the cost rate was reduced across the board. The control fees were significantly reduced: the company conscientiously implemented the gradual implementation of development requirements, focused on the annual goal, and achieved “more than half of the time, half of the tasks.

In the first half of the year, the company completed delivery of 21 ships / 333.

One million tons of deadweight tons, 55 tons of annual plan completed.

68%; repair of 109 ships / 5 completed.

73 trillion, output value completed 78 of the annual plan.

52%; 93 diesel engines / 185 were completed.

340,000 horsepower, the number of power to complete the annual plan of 48.

41%; in terms of mechanical and electrical equipment business, the company achieved output value 6.

00 ppm, 2019H1 company has fully achieved the goal of “more than half the time, more than half the task”.

In terms of fee control, the period fee for 2019H1 is 7.

64 ppm, a reduction of 10 per year.

35%, of which sales expenses / R & D expenses / administrative expenses / financial expenses are 0.

88/3.

48/4.

18 / -0.

90 trillion, a short-term change of 19.

33% / 22.

21% /-1.

07% /-225.

02%, the expense ratio is 0.

90% / 3.

56% / 4.

27% /-0.

92%, a ten-year change of -0.

07 / -1.

25 / -0.

17 / -1.

85pct, of which the increase in sales expenses was mainly due to the increase in the company’s product warranty fees, and the significant decline in financial expenses was mainly due to the declining average expenditure of bank expenditures and the decline in index expenditures, while the incremental increase in US dollar deposits increased earnings.

Asset restructuring and forging assembly listed platform merged with North and South Ship merger expectations, the company’s industry substitution is highlighted: On August 15, 2019, the company released a major asset reorganization adjustment plan, put Hudong Heavy Machinery, injected Jiangnan Shipbuilding, Guangzhou Shipbuilding International, and Huangpu Wenchong.After the reorganization is completed, the company will become a listing platform for ship assembly of subsidiary ships of CSSC.

In addition, the North-South ship merger is expected to rise, and it is expected to generate excess returns based on changes in the estimates of previous military asset injections.

Focusing on naval construction, the company’s warship business is expected to welcome 100 billion market space: Currently, it is gradually promoting the modernization of military equipment and building a “blue water navy”. The military budget has been increasing against the trend.There is a military budget of 1.

$ 19 trillion, up 7 before.

5%, and the continuous adjustment of the military spending structure to the equipment upgrade, the future military equipment is heading to the inflection point, the internal aircraft carrier and supporting ship market in the next 10 years or release over 100 billion space.

In terms of civil ships, high-end and environmentally-friendly ships provide broad market space, and the company’s competitiveness is strong: under the background of structural overcapacity, high-end ships have become indispensable, and the company has made major breakthroughs in high-end ships.China Shipbuilding Carnival Cruise Line Co., Ltd.’s 2 + 4 luxury cruise ship orders set a record for the construction of the 北京夜网 first large cruise ship in China, and won the last pearl in the crown of the shipbuilding industry.

In addition, the company has successively developed more than 20 ultra-large tankers (VLCC), 8 in recent years.

50,000 cubic meters large-scale liquefied gas carrier (VLGC), 400,000 dwt ultra-large ore carrier (VLOC), wood chip ship, MR oil tanker, dump ship and other special vessels. The company has a rich product line in the high-end field and has the most core competition.The future performance of civil ship business can be expected.

In addition to high-end ship types, environmental protection ship types are strongly advocated to replace the existing ship types. The newly injected subsidiaries of the company, Guangchuan International and Huangpu Wenchong, have rich experience in the research and development of environmental 西安耍耍网 protection ship types.

The ultra-large ore vessel “Mafadi” manufactured by Guangzhou Shipyard International Co., Ltd. can reduce hundreds of disposable iron drums each time, which can effectively avoid the problem of hazardous waste accumulation and disposal. The environmentally friendly container ship being built by Huangpu Wenchong meets the current IMO Tier III nitrogen emission environmental protection requirements are the “benchmark products” of the current green world.

Through years of accumulated manufacturing experience and R & D, the company will have significant advantages in the competition of high-end ships and environmental protection ships in the future.

Investment suggestion: The company’s civilian ships will develop high-end ships, military ships are expected to meet the market space of 100 billion yuan, and the future performance of asset reorganization is expected to be further released.According to our model calculations, the net profit attributable to mothers is expected to be 5 in 2019-2021.

5.1 billion, 6.

6.8 billion, 9.

650,000 yuan, EPS is 0.

40, 0.

48, 0.

70 yuan, corresponding to PE is 56 times, 46 times, 32 times.

Risk reminder: Asset restructuring progress is less than expected risk; naval defense construction is less than expected risk; economic downturn and civilian ship recovery is less than expected risk; exchange rate change risk

Jianfa shares (600153): Real estate enters the settlement cycle, dividend yield is at historically high levels and repeatedly outperforms the industry

Jianfa shares (600153): Real estate enters the settlement cycle, dividend yield is at historically high levels and repeatedly outperforms the industry

Company status We recently invited Jianfa to jointly participate in the NDR (Reverse Roadshow of Listed Companies) in Shenzhen and Shanghai, during which investors and investors conducted in-depth exchanges. The main points are as follows: Comment 1. Excellent corporate culture and good incentive mechanism:The controlling shareholder of Jianfa Development Co., Ltd. is Xiamen State-owned Assets Supervision and Administration Commission, which is a local state-owned enterprise. It is cited as a more flexible management mechanism of central enterprises. It has two sets of talent recruitment mechanisms in the market track and the system, which are measured in the reduction of financing costs of private enterprises.

At present, the company has two real estate subsidiaries, Jianfa Real Estate and Lianfa Real Estate, and has 600-700 supply chain subsidiaries. The annual salary of the leaders of outstanding subsidiaries can even reach millions.

2. Real estate business enters the settlement cycle: After 2017, Jianfa and Lianfa Real Estate entered a period of high sales growth (contracted sales amounted to US $ 45.8 billion). According to the sales-to-settlement cycle, it usually takes 2 years. We expect real estate business settlement income toReaching 400 trillion, sales revenue will reach 1,000 trillion.

The net profit margin of the Jianfa subsidiary real estate project is relatively stable, about 10%. After deducting minority shareholders’ profits and losses, we expect that the real estate business (excluding primary development) in 2019 will contribute $ 2.5 billion to the net profit of the mother (compared to the contribution in 2018)200,000 yuan).

3. The first-level land development implies a net profit of more than 5 billion tons: the area of first-level land development that has not yet been transferred is about 930,000 square meters, of which two pieces of land have been demolished 成都桑拿网 and reorganized. We expect to identify one piece of land in 2019.Land development income will contribute 700 million US dollars to the net profit of the mother. In 2020, the first-level land development income of another land will also be recognized, and it will also contribute about 700 million net profit to the mother.

4. Jianfa International will undertake new residential real estate projects inside Jianfa Real Estate, while Jianfa Real Estate will focus on the first-level land development and commercial real estate areas: Jianfa International is a grand company of Jianfa Real Estate, a subsidiary of Jianfa Real EstateFor the listing platform of Hong Kong stocks, CCB has expanded its financing channels. At present, CCB International affiliates owns 70% of the development projects of CCB Real Estate.

5. The supply chain 杭州桑拿网 business will maintain a steady growth of about 10%: bulk supply chains are the company’s traditional strengths, and we expect the company to expand its market share in the consumer supply chain business in the future.

Estimates suggest that we maintain profit for 2019 / 20e44.

6/52.

7 trillion, corresponding to a net profit growth rate of -4 in 2019/20.

6% and 18.

2%.

The current advantage is 8.

96 yuan, corresponding to May 2019/20.

7/4.

8 times P / E.

We re-run the industry rating and maintain our target price of 12.

1 yuan (corresponding to 35% growth space), corresponding to July 2019/20.

7/6.

5 times P / E, the dividend yield in 2019 is about 5.

3%, which is at a historical high of more than 20 years after listing, and has a stable return property.

The risk adjustment policy has become stricter; interest rates in the commodity market have fluctuated.

How to avoid the fate of boiled frogs in warm water

How to avoid the fate of “boiled frogs in warm water”

You can apply them in any field.
Whether it is sales communication, goal setting, time management, or leadership organization, these principles and laws can be applied.
  Six General Laws of Psychology 1. Firmly Believing in Laws When you have 10,000 percent belief in something, it will eventually become a fact.
  2. The Law of Expectations When we are expecting something very strongly, what we expect often appears.
  3, the law of emotion “rational thinking” is also an emotional state, so people are 100% emotional animals, and decisions at any time are emotional decisions.
  4. Law of Attraction When your mind is focused on a certain field, people, things and things related to this field will be attracted to you.
  5. The Law of Specialization Only when you specialize in one area will your field grow exceptionally.
So no matter what industry you are in, you must aim to be the top of the industry.
  6, the law of inertia As long as you can continue to strengthen it, it will eventually become a habit.

Eat dinner like this, the more you eat, the more you hurt!

Almost everyone is recruited?

Eat dinner like this, the more you eat, the more you hurt!
Almost everyone is recruited?

Health Xiaobian shouted every day, “Breakfast is good, lunch is full, dinner is less”, but for most Chinese families, dinner is still a “meal” for a small family reunion.

Dinner can be used without a provincial, but the method of eating must be careful, in order to eat healthy and nutritious, otherwise eating the wrong dinner, easy to cause disease.

Dinner 7 “not suitable” (1) Not too late The best dinner time is 18:00?
20:00, not too late.

Otherwise, it is easy to get a stone after eating dinner.

Because of the slow state of blood flow and the frequency of urination, the high concentration of calcium salt stays in the body, and it combines with uric acid to form calcium oxalate. When calcium oxalate accumulates to a certain concentration, it is easy to form stones.

(2) Not too sweet Some people like to eat sweets after dinner, but too sweet things, it is easy to burden the digestion of the stomach; In addition, less activities after dinner, the sugar in the sweets is difficult to break down, will be directly converted intoOh, it is easy to cause obesity.

Similarly, people have a small amount of activity at night, and don’t eat too much, especially in middle-aged and elderly people, so as not to repeatedly stimulate the secretion of insulin and increase the chance of diabetes.

(3) Should not be too spicy dinner If you eat a lot of pepper, garlic and raw onions and other spicy food, it is easy to make the stomach produce a burning sensation, leading to gastroesophageal reflux or constipation, dry stool, indigestion, etc., thus disturbing sleep, it is recommendedDon’t eat too salty and spicy at dinner.

(4) Not too greasy dinner, often greasy food foraging, will increase the body’s cholesterol content, excessive cholesterol accumulates on the blood vessel wall, and in the long run, it will cause arteriosclerosis and coronary heart disease.

Studies have found that people who regularly eat for dinner have a higher blood fat than those who regularly eat vegetarian food?
4 times, the probability of suffering from high blood pressure and high blood fat is greatly improved.

(5) should not drink excessive drinking before going to bed, resulting in a lot of harmful substances in the wine stored in the body, poisoning the body, damage the retina, reduce resistance, avoid snoring and sleep apnea syndrome significantly increased.

It is recommended that you try not to drink alcohol within 4-6 hours before going to bed. If you have to drink, you must drink green tea to hangover after drinking, or drink a cup of warm milk to protect the gastric mucosa.

(6) It is not advisable to drink meat soup. Some people do not want to eat rice at night. They usually use broth as a dinner, but ribs, trotters and other high content are not easy to decompose and digest. Three high patients, gout patients, and poor stomach are not suitable for evening.It is recommended to eat meat soup, it is recommended to eat at noon, and should also remove most of the oil.

(7) It is not advisable to eat foods that are not easy to digest. At night, the stomach needs mild digestion. Cold and cold foods and dumplings. The rice cakes are hard and hard. After entering the stomach, it will directly affect the work of the stomach, making the digestive activities extremely exciting and easy to cause.Acute and chronic gastritis and other stomach diseases.

At the same time, some foods that produce impurities in the digestion process, such as beans, potatoes, taro, green broccoli, etc., will cause bloating, and should not be eaten so as not to interfere with normal sleep.

Recommend a delicious nutritious dinner!

Fish loofah soup: home often one soup[material]1 squid, 200 grams of loofah, ginger, salt, chicken, cooking wine, pepper, the right amount.

[practice]squid cleaned up, cut into small pieces; loofah peeled, washed, cut into sections.

Add appropriate amount of water to the pot, put the loofah, squid and ginger into the pot and pour in the cooking wine.

Bring the fire to a boil. When the soup is white, switch to a small fire and cook until the fish is cooked. Add salt, chicken, and pepper.

[Efficacy]Loofah vitamin B content is high, which is conducive to children’s brain development and brain health of middle-aged and old people; squid meat is tender and delicious, nutritious, high in protein content, and contains calcium, phosphorus, iron and other minerals and multivitamins.
This soup is nutritious and delicious, which is good for your health and beauty.

[Improve nutrition]If you are making squid soup, you can also fry the squid first, but whether it is fried or not fried, you should remember to cook it with high heat so that the nutrients in the squid can be extracted and made into white soup.The fish soup is completely nutritious and more delicious.

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